Mass concentration of copper in serum/plasma (total serum copper)

Why Is This Test Done?

Your healthcare provider may order this test to check for copper deficiency, which can occur due to conditions like liver disease, malabsorption disorders, or certain medications. It may also be used to monitor copper levels in people with inherited copper metabolism disorders or those receiving copper supplements. Additionally, elevated copper levels might be investigated in cases of Wilson’s disease or other copper-related disorders.

What Does the Result Mean?

Low copper levels might suggest nutritional deficiencies, liver problems, or conditions that interfere with copper absorption. High levels could indicate liver disease, Wilson’s disease, or other metabolic issues. However, reference ranges can vary, so your results will be interpreted by your doctor in the context of your overall health.

Common Conditions Monitored

This test is often used to monitor copper metabolism disorders, such as Wilson’s disease, where the body fails to properly regulate copper. It may also help diagnose or manage conditions affecting copper absorption or storage, like cirrhosis or certain genetic disorders.

Sample Collection and Preparation

A blood sample is drawn from a vein in your arm. The sample is collected in a tube that separates serum (the liquid part) or plasma (the liquid part after clotting factors are removed). The sample is then sent to a lab for analysis using a high-performance liquid chromatography (HPLC) method to measure copper concentration accurately.