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Mass concentration of purine metabolites in urine (specifically, xanthine and hypoxanthine)

Published: August 9, 2026Updated: August 16, 2026

This test measures certain waste products from your body’s breakdown of purines, which are compounds found in foods and produced naturally in your cells. It helps assess how well your kidneys are filtering these substances.

Quick summary

["This test may help diagnose or monitor kidney function or conditions affecting purine metabolism."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
78855-4
Short code
m-CPP Ur-mCnc
Synonyms
m-CPP Ur-mCnc
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms of kidney problems, such as frequent urination, swelling, or fatigue. It could also be part of a broader evaluation for conditions like gout, kidney stones, or metabolic disorders linked to purine metabolism.

What to Expect Before the Test

No special preparation is needed. You’ll provide a urine sample, typically collected over a 24-hour period, though some labs may use a single random sample. Drink plenty of water to ensure adequate urine volume if instructed.

What the Results Mean

Higher-than-normal levels may indicate kidney issues or conditions that increase purine production, such as certain cancers or genetic disorders. Lower levels might suggest dehydration or other metabolic factors. Results are interpreted in context with your overall health and symptoms.

Common Conditions Monitored

This test is sometimes used to monitor kidney function, especially in cases of suspected nephrolithiasis (kidney stones), chronic kidney disease, or metabolic disorders like Lesch-Nyhan syndrome, which affects purine metabolism.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Urine purine metabolite mass concentration

Frequently asked questions

What does a high or low result mean?
High levels may suggest kidney problems or conditions that increase purine production, such as certain cancers or metabolic disorders. Low levels could indicate dehydration or other metabolic factors, but results are always reviewed with your overall health picture.
Does diet affect this test?
Dietary purines (found in meat, fish, and some vegetables) can influence purine metabolite levels. If instructed, avoid high-purine foods for a few days before testing to get a clearer picture of kidney function.
How often is this test repeated?
Your provider will determine frequency based on your symptoms and test results. It may be repeated if kidney function or metabolic health needs ongoing monitoring, such as in chronic kidney disease or certain genetic conditions.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy