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Microalbumin-to-Creatinine Ratio in Urine (24-hour collection)

Published: August 9, 2026Updated: August 16, 2026

This test measures tiny amounts of albumin (a protein) in your urine compared to creatinine (a waste product from muscles). It helps check for early kidney damage or diabetes-related kidney problems.

Quick summary

["Assesses kidney function and diabetes-related kidney risks over a full day’s urine output."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
111979-1
Short code
Mcro mrph cls cncr tmr Blry tr Endscpy
Synonyms
Mcro mrph cls cncr tmr Blry tr Endscpy
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
endoscopy
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters for Your Health

Your kidneys normally filter waste and excess protein from your blood. If they struggle, small amounts of albumin can leak into urine. This test detects early signs of kidney issues, especially in people with diabetes, high blood pressure, or family history of kidney problems. It’s often used alongside other tests to monitor kidney health over time.

How the Test Works

You’ll collect all your urine for 24 hours and return it to the lab. The lab then measures albumin and creatinine levels in your urine sample. The ratio helps identify if your kidneys are working as they should, especially in people at higher risk for kidney problems.

What to Expect Before the Test

No special preparation is needed, but drink plenty of water to help your kidneys filter properly. Avoid certain medications (like NSAIDs) that may affect kidney function, but always check with your doctor first. If you have diabetes, follow your usual routine unless instructed otherwise.

Common Results and Next Steps

Results are typically compared to your individual baseline or risk profile. Elevated ratios may signal early kidney damage, prompting further testing or adjustments to your treatment plan. Your doctor will discuss findings with you and may recommend follow-ups or lifestyle changes.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Microalbumin:Cr Urine Ratio

Frequently asked questions

What does a high or low ratio mean?
A high ratio may indicate early kidney damage or diabetes-related kidney disease. A low ratio suggests kidneys are filtering normally, but this doesn’t rule out other kidney issues—your doctor will interpret results in context with your medical history and other tests.
How often should I get this test?
Your doctor will determine how often based on your health, risk factors (like diabetes or high blood pressure), and test results. Some people with chronic conditions get this test yearly or more frequently to monitor kidney health over time.
Can I eat or drink anything before the test?
You can eat and drink normally, but drink extra water to help your kidneys filter urine properly. Avoid alcohol or large amounts of caffeine, as they may affect urine composition. Always follow your doctor’s specific instructions.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy