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Nitric Oxide in Whole Blood (Stable Isotope Dilution Mass Spectrometry)

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of nitric oxide, a naturally occurring chemical in your blood that helps regulate blood pressure and blood flow. Nitric oxide is produced by your body in response to certain conditions and can be studied to understand vascular health.

Quick summary

["Nitric oxide helps maintain healthy blood vessels and may be checked if you have concerns about circulation or blood pressure issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
90502-6
Short code
MDSV30RAIV1172IDENTIFICATIONINFORMATIONNTST
Synonyms
—
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
cms-assessment
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like high blood pressure, poor circulation, or conditions affecting blood vessels. It might also be used in research or specialized studies involving nitric oxide metabolism.

What to Expect Before the Test

No special preparation is needed. You’ll provide a small sample of whole blood drawn from a vein, similar to other blood tests. If you’re on blood thinners, let your provider know before the test.

What the Results Mean

Results help assess how well your body produces nitric oxide, which can indicate whether your blood vessels are functioning normally. Abnormal levels may suggest underlying vascular or cardiovascular concerns.

Common Conditions Monitored

This test is less commonly used in routine care but may be part of advanced studies for conditions like peripheral artery disease, vascular dysfunction, or research into nitric oxide’s role in health.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical significance: Elevated or reduced nitric oxide levels may signal vascular issues, such as atherosclerosis or endothelial dysfunction, but interpretation depends on clinical context and other test results. It’s often used in specialized settings like clinical trials or research.

Short name

Nitric Oxide (NO) Blood Test

Frequently asked questions

Will this test show if I have high blood pressure?
Not directly. While nitric oxide plays a role in blood pressure regulation, this test alone doesn’t diagnose hypertension. It may be part of a broader evaluation if vascular health is suspected.
How long will it take to get my results?
Results typically arrive within 1–3 business days, depending on lab processing and your healthcare provider’s workflow. Follow-up may require additional testing or discussion with your provider.
Can I eat or drink before this test?
No restrictions apply. You can eat, drink water, and take medications as usual. Whole blood tests don’t require fasting.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy