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Transplacental transfer protein (or fetal protein) evaluation

Published: August 9, 2026Updated: August 16, 2026

This test measures levels of proteins that cross from mother to fetus during pregnancy, helping assess fetal health and potential risks.

Quick summary

["This screening helps monitor fetal development and detect possible complications early."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
83799-7
Short code
MD Trnsplt cand eval nte
Synonyms
MD Trnsplt cand eval nte
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
physician
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Doctors may recommend this test if you have certain risk factors for pregnancy complications, such as high blood pressure, diabetes, or a history of miscarriage. It can also be part of routine prenatal care in some cases to check fetal well-being.

What to Expect Before the Test

You’ll typically provide a blood sample from a vein in your arm. The test involves a simple venipuncture procedure, and you may feel a brief pinch or pressure. No special preparation is needed.

What the Test Measures

The test evaluates levels of proteins that cross from your bloodstream into the placenta and then into the fetal circulation. These proteins can indicate how well the placenta is functioning and whether the fetus is receiving adequate nutrients and oxygen.

What the Results Mean

Results are used to identify potential issues like placental insufficiency, fetal growth restrictions, or other conditions that may require further medical evaluation or intervention. Your healthcare provider will discuss the results with you and determine the next steps.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Fetal Protein Screening

Frequently asked questions

How soon will I get my results?
Results are usually available within a few days to a week, depending on lab processing times. Your healthcare provider will contact you to discuss the findings and any follow-up actions needed.
What does a low or high protein level indicate?
Low levels may suggest problems with placental function or fetal health, while high levels could indicate other conditions that need further investigation. Your doctor will interpret results in the context of your pregnancy history and overall health.
Can I take anything special to prepare for this test?
No special preparation is required. However, inform your healthcare provider about any medications you’re taking or if you have any concerns about the test.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy