Mean Chromosome Band Resolution (Blood Karyotyping)
This test evaluates the clarity and detail of chromosomes in your blood sample, often used to assess genetic structure during prenatal or diagnostic evaluations.
["Understanding your blood’s chromosome detail can help diagnose genetic conditions or guide reproductive health decisions."]
Key facts at a glance
- LOINC
- 101239-2
- Short code
- Mean chr band resolution Bld/T Banding
- Synonyms
- Mean chr band resolution Bld/T Banding
- Category
- chemistry
- Sample
- whole-blood
- Container
- Lavender-top (EDTA)
- Units
- N/A
- Critical range
- 0.5 N/A – —
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- banding
- Specimen volume
- 3 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
The test analyzes the resolution (level of detail) of chromosomes in blood cells, typically visualized through banding patterns created by staining. Higher resolution means finer details of chromosome structure are visible, aiding in identifying abnormalities like translocations, deletions, or duplications.
Why It’s Done
This test is often performed during prenatal care (e.g., for screening in pregnancies at higher risk) or when evaluating suspected genetic disorders, inherited conditions, or unexplained developmental delays. It may also be used in research or specialized diagnostic settings.
Sample and Process
A blood sample is drawn, and chromosomes are prepared on a microscope slide. Special staining techniques (e.g., Giemsa banding) highlight chromosome bands, which are then examined under a microscope for resolution quality. Results are qualitative (descriptive) rather than numeric.
What the Results Mean
Results describe the clarity of chromosome bands (e.g., ‘high resolution’ or ‘poor resolution’). High resolution typically indicates normal or well-defined chromosomal structure, while poor resolution may suggest technical issues or limitations in sample preparation.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Short name
None
Frequently asked questions
High-resolution chromosome analysis is critical for diagnosing genetic disorders, identifying carrier status for inherited conditions, or confirming prenatal diagnoses (e.g., Down syndrome). It may also guide decisions about genetic counseling or reproductive options.
Common reasons for this test include prenatal screening, genetic counseling for suspected inherited conditions, or research involving chromosomal studies. It is not typically ordered for routine health checks.
No fasting is required, but your doctor may specify timing for optimal sample quality. Blood is drawn from a vein in your arm.
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy