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Serum or Plasma Creatinine Concentration (Qualitative or Quantitative)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of creatinine, a waste product from muscle metabolism, in your blood or plasma. It helps assess kidney function.

Quick summary

["A creatinine test helps check how well your kidneys are filtering waste from your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
92968-7
Short code
mecA+mecC Islt/Spm Ql
Synonyms
mecA+mecC Islt/Spm Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
molgen
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test to evaluate kidney health, monitor chronic kidney disease, detect early kidney problems, or assess kidney function before certain treatments or surgeries. It can also help determine if you need dialysis or other kidney support.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for 8–12 hours before the test if it’s part of a more complex evaluation. Drink plenty of water the day before to ensure accurate results.

How the Test Is Performed

A blood sample is drawn from a vein (typically in your arm) by a healthcare professional. The sample is sent to a lab for analysis using methods like enzymatic or nephelometric techniques.

What the Results Mean

Results are compared to standard reference ranges, but exact values depend on lab equipment and patient factors. High levels may indicate kidney issues, while very low levels could suggest muscle disorders or dehydration.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Creatinine levels are a key marker for kidney function because they reflect how well your kidneys filter blood. Elevated levels often signal impaired kidney function, early-stage kidney disease, or conditions like diabetes or heart disease. Low levels may warrant further investigation to rule out muscle problems or dehydration.

Short name

Creatinine Level (Serum/Plasma)

Frequently asked questions

How often should I get this test?
The frequency depends on your health condition. If you have kidney disease, your doctor may recommend testing every few months or annually. Healthy individuals may only need it if they have risk factors (e.g., high blood pressure, diabetes) or if undergoing certain procedures.
What causes creatinine levels to be too high?
High creatinine levels can result from kidney disease, dehydration, severe muscle damage, or conditions like heart failure or diabetes. Chronic kidney disease, poor blood flow to kidneys, or certain medications may also contribute.
Can diet affect creatinine levels?
Dietary protein intake can influence creatinine levels, but the effect is usually small. Excessive protein or muscle-building diets may temporarily raise levels, while dehydration can also spike them. Your doctor may adjust your diet if needed for kidney health.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy