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Epinephrine (Adrenaline) in Plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of epinephrine, a hormone produced by your adrenal glands, in your blood plasma. Epinephrine helps regulate your body’s response to stress, anxiety, or physical activity.

Quick summary

["Epinephrine levels can help diagnose or monitor conditions linked to abnormal hormone release."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
19576-8
Short code
Me-ePHEDrine CtO Ur Cfm-mCnc
Synonyms
Me-ePHEDrine CtO Ur Cfm-mCnc
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
confirm
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like rapid heartbeat, high blood pressure, or severe anxiety that suggest your body is releasing too much epinephrine. It may also be used in cases of suspected adrenal gland disorders, pheochromocytoma (a rare tumor), or during stress-related conditions like panic attacks or severe allergies.

What to Expect Before the Test

No special preparation is usually needed. You may be asked to fast for 8–12 hours before the test if it involves a blood draw, but this depends on your provider’s instructions. Avoid caffeine or nicotine for several hours before testing, as they can affect results.

How the Test Is Performed

A healthcare professional will draw blood from a vein in your arm using a small needle. The blood sample is then sent to a lab for analysis using a sensitive immunoassay method to detect epinephrine levels.

What the Results Mean

Results are typically reported as a concentration in nanograms per milliliter (ng/mL). High levels may indicate conditions like pheochromocytoma, severe anxiety, or adrenal gland tumors. Low levels might suggest adrenal insufficiency or other hormonal imbalances. Your provider will interpret results in the context of your symptoms and medical history.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Plasma Epinephrine

Frequently asked questions

What could elevated epinephrine levels suggest?
Elevated epinephrine levels can signal conditions such as pheochromocytoma (a tumor affecting hormone production), severe anxiety disorders, or hyperthyroidism. It may also appear in response to extreme stress, trauma, or certain medications.
What could low epinephrine levels suggest?
Low epinephrine levels might indicate adrenal insufficiency (Addison’s disease), certain medications that suppress hormone release, or chronic stress-related exhaustion. It’s important to discuss symptoms like fatigue, dizziness, or low blood pressure with your provider.
How often should I get this test?
This test is usually ordered as needed based on symptoms or medical concerns. Follow your healthcare provider’s guidance—some patients may need repeat testing if conditions like pheochromocytoma are suspected or monitored over time.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy