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Epinephrine (serum/plasma mass concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of epinephrine, a powerful hormone and neurotransmitter, in your blood. Epinephrine helps regulate your body’s response to stress, fear, or physical activity.

Quick summary

["Epinephrine levels can help diagnose or monitor conditions affecting your adrenal glands or stress responses."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
17273-4
Short code
Me-ePHEDrine Ur-aCnc
Synonyms
Me-ePHEDrine Ur-aCnc
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why Might You Need This Test?

Your doctor may order this test if you have symptoms like high blood pressure, rapid heartbeat, anxiety, or other signs of adrenal gland issues (e.g., pheochromocytoma). It may also be used to check for stress-related hormone imbalances or after trauma.

What to Expect During the Test

A blood sample is taken from a vein in your arm. You may feel a slight pinch, but it usually doesn’t cause discomfort. The sample is sent to a lab for analysis.

Factors That Could Affect Results

Epinephrine levels can be influenced by recent stress, exercise, caffeine, or certain medications. Avoiding these before testing can help get more accurate results.

Common Conditions Monitored

This test is often used to diagnose or evaluate conditions like pheochromocytoma (a tumor affecting hormone production), adrenal insufficiency, or stress-related hormone disorders.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Epinephrine plays a critical role in your body’s fight-or-flight response. High levels may indicate overactive adrenal glands or stress-related conditions, while low levels could signal adrenal gland dysfunction or other health issues.

Short name

Serum/plasma epinephrine

Frequently asked questions

What triggers a high epinephrine reading?
High epinephrine levels can be caused by severe stress, anxiety, physical exertion, certain medications, or conditions like pheochromocytoma. Your doctor will consider your full medical history and symptoms.
How soon can I expect results?
Results typically take 1–3 business days, depending on your lab’s processing time. Your doctor will contact you once they’re ready to discuss the findings.
Can I take anything before the test?
Avoid caffeine, nicotine, or intense exercise 24 hours before testing. Follow any specific instructions your doctor provides to ensure accurate results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy