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Mental Health Transdiagnostic Phenotype Evaluation (Serum/Plasma)

Published: August 9, 2026Updated: August 17, 2026

This test measures biomarkers linked to mental health conditions, helping assess potential underlying biological factors in symptoms like mood, cognition, or stress responses.

Quick summary

["This test may help identify biological markers associated with mental health concerns, though results are not a standalone diagnosis."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
84216-1
Short code
Mental health Trnsplt cand eval nte
Synonyms
Mental health Trnsplt cand eval nte
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
7
Ref high
56
Critical range
— – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
mental-health
CPT
84484
SNOMED
302773008
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The evaluation includes a panel of substances that may reflect physiological processes tied to mental health, such as neuroactive compounds, stress hormones, or metabolic markers. Results are interpreted in the context of clinical presentation and symptoms.

How the Sample Is Collected

A blood sample is drawn from a vein in your arm. You may feel a slight pinch, but it typically doesn’t cause discomfort. The sample is processed into serum or plasma for testing.

What to Expect Before the Test

No special preparation is needed, but avoid heavy meals or caffeine 2 hours before your appointment. If you’re on medications, inform your provider before testing.

How Results Are Used

These results are used alongside your medical history, symptoms, and psychological evaluation to identify patterns that may inform treatment planning, such as therapy or medication adjustments.

Reference range

Adult males: 7-56 U/L; Adult females: 7-43 U/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

While no single biomarker definitively diagnoses mental health conditions, certain patterns in these markers may correlate with conditions like depression, anxiety, or stress-related disorders. They can help rule out physical causes of symptoms or guide targeted interventions.

Short name

Mental Health Biomarker Profile

Frequently asked questions

Why might my doctor order this test?
Your doctor may recommend this test if you have persistent symptoms of mental health conditions, unexplained physical symptoms, or if they suspect an underlying biological factor contributing to your concerns.
Will this test replace therapy or medication?
No, this test provides additional information but isn’t a substitute for professional evaluation. Results are used alongside clinical judgment to tailor support, such as therapy or treatment plans.
What if my results are abnormal?
Abnormal results will be discussed with you by your healthcare provider. They may recommend further testing, lifestyle changes, or adjustments to your treatment plan based on the findings.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy