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24-Hour Urine Mephenytoin Excretion Rate

Published: August 9, 2026Updated: August 16, 2026

This test measures how much of a medication called mephenytoin your body eliminates in urine over 24 hours. It helps assess liver function and how well your body processes certain drugs.

Quick summary

["This test helps doctors check liver function and drug metabolism."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
3810-9
Short code
Me-phenidate 24h Ur-mRate
Synonyms
Me-phenidate 24h Ur-mRate
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Ref low
20
Ref high
400
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82670
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order this test if they suspect liver problems or if you’re taking medications that require liver metabolism. It can also help monitor how your body handles specific drugs, such as antiepileptic medications.

What Does the Test Involve?

You’ll collect all your urine for a full 24-hour period in a special container. The sample is then sent to a lab for analysis to determine the amount of mephenytoin excreted.

Sample Collection Process

To prepare, empty your bladder at the start of the 24-hour period (e.g., midnight). Collect every urine output—including first-morning urine—into the container. Replace the lid and refrigerate if needed. Finish at the same time the next day.

What to Expect During Testing

No special preparation is needed beyond collecting urine as directed. You may experience mild discomfort if you’re taking mephenytoin, but side effects are usually temporary.

Reference range

Premenopausal: 20-400 pg/mL; Postmenopausal: <30 pg/mLN/A

Specimen: urine

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: This test is primarily used to evaluate liver function and drug metabolism. Abnormal results may indicate liver impairment, poor drug clearance, or other metabolic issues. It’s less common but can be critical in specific cases, such as monitoring patients on certain antiepileptic drugs.

Short name

24h Urine Mephenytoin Rate

Frequently asked questions

What causes mephenytoin to be tested?
Mephenytoin is a medication used to treat seizures. Your doctor may order this test if you’re taking it or if they suspect liver problems that could affect how well your body processes the drug.
How long does it take to get results?
Results typically take 1–3 business days, depending on lab processing times. Your doctor will contact you once they have the results.
Can I drink alcohol before this test?
Yes, you can drink alcohol normally unless your doctor advises otherwise. Alcohol does not interfere with urine collection but may affect liver function indirectly.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy