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Methionine Metabolite Profile (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures levels of certain compounds involved in methionine metabolism, which helps assess how well your body processes this essential amino acid.

Quick summary

["Understanding your methionine metabolism can help identify potential nutrient deficiencies or metabolic disorders."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
72262-9
Short code
MetHgb CSF-sCnc
Synonyms
MetHgb CSF-sCnc
Category
hematology
Sample
csf
Container
Sterile tube
Units
N/A
Ref low
12
Ref high
17.5
Critical range
7 N/A – 20 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
85018
SNOMED
900000000000003004
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like fatigue, neurological issues, or if you have conditions such as homocystinuria, liver disease, or certain genetic disorders. It may also be used to monitor treatment for metabolic conditions.

No special preparation is typically needed, but you may be asked to fast for a few hours before the blood draw if your test includes fasting samples. Wear comfortable clothing and plan for the time it takes to get your blood drawn.

A healthcare professional will insert a small needle into your arm to draw blood. You may feel a slight pinch, but it usually doesn’t cause significant discomfort. The blood sample will be sent to a lab for analysis.

Your results will show the concentrations of specific metabolites in your blood. These levels can help determine if there are imbalances in your metabolism that may require further medical evaluation or treatment.

If your levels are outside expected ranges, your doctor may recommend additional tests or treatments to address potential deficiencies or metabolic issues.

Abnormal results might be linked to conditions such as homocystinuria, liver dysfunction, or certain genetic metabolic disorders. High levels may indicate impaired metabolism, while low levels could suggest nutritional deficiencies or other metabolic issues.

Abnormal results may prompt further investigation, including genetic testing or dietary adjustments, to manage underlying health concerns.

Reference range

Adult males: 13.5-17.5 g/dL; Females: 12.0-16.0 g/dLN/A

Specimen: csf

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Methionine-related metabolites

Frequently asked questions

What does a high level of these metabolites mean?
High levels may suggest impaired metabolism of methionine or related pathways. This could be due to genetic disorders, liver disease, or other metabolic conditions. Your doctor will discuss the findings with you and may recommend further tests or treatments.
Low levels might indicate a deficiency in essential nutrients or enzymes involved in methionine metabolism. This could be caused by dietary factors, malabsorption issues, or certain genetic conditions. Your healthcare provider will evaluate your results in the context of your overall health.
Yes, diet can influence metabolite levels. For example, consuming foods high in methionine or certain supplements may temporarily alter your test results. If fasting is required, follow your provider’s instructions to ensure accurate results.
The frequency of this test depends on your medical condition and treatment plan. Your healthcare provider will determine how often you need follow-up testing based on your individual needs and symptoms.
If you have questions or concerns about your test results, discuss them with your healthcare provider. They can explain the findings in detail and help you understand the next steps, whether that involves lifestyle changes, further testing, or medical treatment.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy