Methionine levels in blood (mass concentration)
This test measures the amount of methionine, an essential amino acid, in your blood. It may be used to assess metabolic function or identify conditions affecting amino acid metabolism.
["This test helps evaluate how well your body processes amino acids and may support diagnosis of metabolic disorders."]
Key facts at a glance
- LOINC
- 2614-6
- Short code
- MetHgb MFr Bld
- Synonyms
- MetHgb MFr Bld
- Category
- hematology
- Sample
- whole-blood
- Container
- Lavender-top (EDTA)
- Units
- N/A
- Ref low
- 12
- Ref high
- 17.5
- Critical range
- 7 N/A – 20 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 85018
- SNOMED
- 900000000000003004
- Specimen volume
- 3 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
Why This Test Might Be Ordered
Your healthcare provider may recommend this test if you have symptoms like fatigue, muscle weakness, or unexplained metabolic issues. It could also be part of a broader evaluation for conditions like homocystinuria or other amino acid metabolism disorders.
What to Expect Before the Test
No special preparation is typically required. You may fast for 8–12 hours before the test if instructed, but always follow your provider’s specific instructions. Bring any medications you’re taking to your appointment.
How the Test Is Performed
A blood sample is drawn from a vein, usually in your arm. The sample is sent to a lab for analysis using a high-performance liquid chromatography (HPLC) method to measure methionine concentration.
What the Results Mean
Results are compared to standard reference ranges for healthy individuals. Abnormally high or low levels may indicate metabolic disorders or other health concerns that need further evaluation.
Reference range
Adult males: 13.5-17.5 g/dL; Females: 12.0-16.0 g/dLN/A
No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Elevated methionine levels can be linked to conditions like homocystinuria or certain genetic disorders affecting amino acid metabolism. Low levels may suggest deficiencies or impaired synthesis pathways. Always discuss results with your healthcare provider for personalized interpretation.
Short name
Methionine Blood Level
Frequently asked questions
What causes abnormal methionine levels?
How long does it take to get results?
Can I eat or drink before this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy