Methionine (Serum or Plasma Mass Concentration)
This test measures the amount of methionine, an essential amino acid, in your blood. It may be used to assess metabolic health or evaluate conditions affecting amino acid metabolism.
["This test helps monitor amino acid balance in your blood."]
Key facts at a glance
- LOINC
- 71883-3
- Short code
- MetHgb MFr.DF Bld
- Synonyms
- MetHgb MFr.DF Bld
- Category
- hematology
- Sample
- whole-blood
- Container
- Lavender-top (EDTA)
- Units
- N/A
- Ref low
- 12
- Ref high
- 17.5
- Critical range
- 7 N/A – 20 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 85018
- SNOMED
- 900000000000003004
- Specimen volume
- 3 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
Why Might This Test Be Ordered?
Your healthcare provider may recommend this test if you have symptoms or conditions linked to amino acid imbalances, such as liver disease, kidney problems, or certain metabolic disorders. It could also be part of routine metabolic screening or monitoring for nutritional deficiencies.
What Does This Test Involve?
A blood sample is drawn from a vein, usually in your arm. The sample is then processed to measure methionine levels using a specialized laboratory technique. The test typically requires fasting, but your provider will specify instructions.
What to Expect Before the Test
Prepare for the test by following any fasting instructions given by your healthcare provider. Avoid smoking or consuming alcohol before the procedure. Wear comfortable clothing and plan for the time it takes to draw blood, which usually takes a few minutes.
What to Expect During the Test
You will sit comfortably while a healthcare professional inserts a small needle into your vein. You may feel a slight pinch, but the procedure is generally quick and painless. Once the blood is collected, the needle is removed, and a bandage is applied.
Reference range
Adult males: 13.5-17.5 g/dL; Females: 12.0-16.0 g/dLN/A
No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
Serum/plasma methionine level
Frequently asked questions
High levels of methionine in the blood may be associated with certain metabolic disorders, liver disease, or kidney dysfunction. Low levels might indicate nutritional deficiencies or other metabolic issues. This test helps diagnose and monitor conditions affecting amino acid metabolism.
A high methionine level could suggest underlying metabolic disorders, liver problems, or conditions that affect how your body processes amino acids. Your healthcare provider will discuss the results in the context of your overall health and any symptoms you may have.
The frequency of this test depends on your medical condition and treatment plan. Your healthcare provider will determine how often you need it based on your individual needs and medical history.
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy