Methionine (Serum or Plasma Mass Concentration)
This test measures the amount of methionine, an essential amino acid, in your blood. It may be ordered to assess nutritional status, metabolic health, or conditions affecting amino acid metabolism.
["Methionine levels help check if your body is getting enough nutrients or if certain metabolic processes are functioning properly."]
Key facts at a glance
- LOINC
- 71881-7
- Short code
- MetHgb MFr.DF BldC
- Synonyms
- MetHgb MFr.DF BldC
- Category
- hematology
- Sample
- whole-blood
- Container
- Lavender-top (EDTA)
- Units
- N/A
- Ref low
- 12
- Ref high
- 17.5
- Critical range
- 7 N/A – 20 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 85018
- SNOMED
- 900000000000003004
- Specimen volume
- 3 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
Why This Test Might Be Ordered
Your healthcare provider may recommend this test if you have symptoms like fatigue, muscle weakness, or unexplained weight changes. It could also be part of a broader evaluation for conditions like liver disease, kidney problems, or nutritional deficiencies, especially in cases where amino acid imbalances are suspected.
What to Expect Before the Test
No special preparation is usually needed, but you may be asked to fast for a few hours before the draw if your test involves a fasting sample. Wear a loose shirt for easy access to your arm.
What the Test Results Mean
Results are interpreted based on your overall health and medical history. Abnormally high or low levels might indicate underlying issues, but your doctor will discuss findings with you.
Common Conditions Linked to Methionine Levels
Elevated levels may be seen in liver disease, certain genetic disorders, or excessive intake of methionine-rich foods. Low levels can occur with malnutrition, kidney disease, or certain metabolic syndromes.
Reference range
Adult males: 13.5-17.5 g/dL; Females: 12.0-16.0 g/dLN/A
No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
Serum/plasma methionine level
Frequently asked questions
How is this test typically collected?
What does it feel like after the blood draw?
Can I eat or drink before this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy