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Methylone and Creatinine, Urine

Published: August 9, 2026Updated: August 16, 2026

A urine test that checks for methylone, a stimulant sometimes called a “designer drug,” and measures creatinine to help assess urine concentration.

Quick summary

["Detecting methylone in urine may indicate recent exposure, while urine creatinine helps determine whether the sample is too dilute for reliable interpretation."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
72794-1
Short code
Methylone/Creat Ur
Synonyms
Methylone/Creat Ur
Category
kidney
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

This test examines a urine sample for methylone, an illegal stimulant chemically related to MDMA (ecstasy). It also measures urine creatinine, which reflects how concentrated the urine is and can help determine whether a low drug result may be affected by dilution.

Why might I need this test?

Methylone testing may be requested when recent drug use is suspected, during emergency evaluation, or for employment, school, legal, or substance-use monitoring. It is not the same as a methadone test, and its availability may vary by laboratory.

How is the test performed?

A urine specimen is collected and analyzed by the laboratory. Screening methods may not detect methylone reliably, so a specific laboratory method or confirmatory testing may be needed. Creatinine is measured to help evaluate the concentration of the specimen.

How do I prepare for the test?

Follow the collection instructions provided by the laboratory or clinician, and do not drink excessive amounts of water beforehand. Tell the clinician about prescription medicines, over-the-counter products, supplements, and other drugs you have recently used, because these can affect interpretation or the testing method.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

A detectable methylone result indicates that methylone was present in the urine and may be consistent with recent use. A negative result does not completely exclude exposure because the detection window depends on the dose, timing, urine concentration, and testing method. Urine creatinine helps show whether a dilute sample may have affected the result. A positive result should be interpreted by a healthcare professional, especially with confirmatory testing.

Short name

Urine methylone and creatinine

Frequently asked questions

Does a positive result mean someone is currently impaired?
No. Urine testing can show recent exposure but cannot by itself determine when the drug was taken or whether the person is currently impaired.
Is methylone the same as methadone?
No. Methylone is a stimulant sometimes called a designer drug, while methadone is a prescription medicine used for pain and opioid-use disorder. A methylone test should not be interpreted as a methadone test.
Why is creatinine measured with methylone?
Urine creatinine helps assess how concentrated the specimen is. A very dilute sample can make an otherwise detectable amount of methylone harder to identify.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy