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Serum or Plasma Creatinine Concentration (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of creatinine, a waste product from muscle breakdown, in your blood or plasma. It helps assess how well your kidneys are filtering blood.

Quick summary

["A creatinine test helps check kidney function and detect early kidney problems."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
15484-9
Short code
M gallisep Ab Ser Ql Aggl
Synonyms
M gallisep Ab Ser Ql Aggl
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
aggl
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Creatinine is a natural byproduct of muscle metabolism and is filtered out of your blood by your kidneys. If your kidneys aren’t working well, creatinine levels can build up in your blood. This test helps doctors monitor kidney health, especially if you have conditions like diabetes, high blood pressure, or a history of kidney disease.

What to Expect Before the Test

You may be asked to fast for a few hours before the test, but this isn’t always required. Bring any medications you’re currently taking, as some may affect results. Avoid strenuous activity or heavy meals before testing.

How the Test Is Done

A healthcare provider will draw blood from a vein in your arm using a small needle. You may feel a slight pinch, but it usually doesn’t cause discomfort. The blood is then sent to a lab for analysis.

What the Results Mean

Results are compared to a reference range, which can vary slightly by lab. Higher levels may indicate poor kidney function, while lower levels might suggest overhydration or muscle loss. Your doctor will discuss your specific results in the context of your health.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Creatinine

Frequently asked questions

What are the normal reference ranges for creatinine?
Normal reference ranges can vary by lab and age. For adults, typical ranges for serum/plasma creatinine are often between 0.6 to 1.2 mg/dL (53–106 µmol/L), but this can differ. Your doctor will interpret results based on your overall health and medical history.
Can dehydration affect creatinine levels?
Yes, dehydration can raise creatinine levels because less water in your blood means more creatinine stays in your system. Staying hydrated can help maintain normal levels, but your doctor will consider other factors when reviewing results.
How often should I get this test?
Your doctor may recommend this test periodically if you have kidney-related conditions, are taking medications that affect kidney function, or are at higher risk for kidney disease. Follow their guidance for scheduling.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy