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Glutamate Receptor 1 (GR1) Antibody, Immunoassay (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures antibodies against glutamate receptor 1, a protein involved in brain signaling. These antibodies may be detected in conditions affecting the nervous system.

Quick summary

["This test helps evaluate potential autoimmune or inflammatory neurological conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
109791-4
Short code
mGluR1 IgG Msmt CSF
Synonyms
mGluR1 IgG Msmt CSF
Category
coagulation
Sample
csf
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like unexplained neurological issues, such as seizures, muscle weakness, or cognitive problems. It could also be part of a broader evaluation for autoimmune disorders affecting the brain or nerves.

What to Expect Before the Test

No special preparation is needed. You’ll provide a blood sample, typically drawn from your arm. If you’re on blood-thinning medication, let your provider know before the test.

What the Test Results Mean

Positive results indicate the presence of GR1 antibodies, which may suggest an autoimmune response targeting brain receptors. However, further testing and clinical correlation are needed to diagnose a specific condition.

Common Conditions Linked to This Test

While GR1 antibodies are less commonly associated with well-defined diseases, they may be linked to conditions like autoimmune encephalitis or other inflammatory neurological disorders. Your provider will discuss findings in the context of your symptoms and medical history.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

GR1 Antibody

Frequently asked questions

How long will I need to wait for my results?
Results are typically available within 1–3 business days, depending on lab processing times. Your provider will contact you with the final report.
Can I fast before this test?
No fasting is required for this blood test. However, inform your provider about any medications or supplements you’re taking, as they may affect results.
What if my results are abnormal?
If results are abnormal, your provider will review them with you and may recommend additional tests or treatments tailored to your symptoms and diagnosis.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy