Glutamate Receptor 1 (mGluR1) Antibody, Immunoassay (Serum/Plasma)
This test measures antibodies against glutamate receptor 1 (mGluR1) in your blood. These antibodies may be linked to certain autoimmune or neurological conditions.
["This test helps identify potential autoimmune responses affecting brain receptors."]
Key facts at a glance
- LOINC
- 93499-2
- Short code
- mGluR1 IgG Titr Ser IF
- Synonyms
- mGluR1 IgG Titr Ser IF
- Category
- coagulation
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 8
- Ref high
- 61
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- if
- CPT
- 82977
- SNOMED
- 3110003
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What Does This Test Measure?
The test detects the presence of mGluR1 antibodies, which are proteins your immune system may mistakenly target. These antibodies can be associated with conditions affecting brain function, such as autoimmune encephalitis or related disorders.
Why Might You Need This Test?
Your healthcare provider may order this test if you have symptoms like unexplained seizures, confusion, memory issues, or other neurological symptoms that suggest an autoimmune response targeting brain receptors.
Sample Collection and Preparation
A blood sample is drawn from a vein in your arm. The blood is processed to separate serum or plasma, which is then tested for mGluR1 antibodies using an immunoassay method.
What to Expect Before the Test
No special preparation is typically needed, but you may be asked to avoid certain medications or supplements that could affect results. Always inform your provider about all medications or supplements you’re taking.
Reference range
Adult males: 8-61 U/L; Adult females: 5-36 U/LN/A
No special preparation required. Avoid fatty meals before the test if possible.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
mGluR1 Antibody
Frequently asked questions
Positive results may indicate an autoimmune condition affecting glutamate receptors, which can disrupt normal brain signaling. This can lead to symptoms like seizures, movement disorders, or cognitive impairments. Further evaluation by a neurologist or specialist may be needed to determine the cause and appropriate treatment.
A positive result suggests the presence of mGluR1 antibodies, which may warrant further testing or evaluation to explore potential autoimmune or neurological conditions. A negative result means no detectable antibodies were found in this sample, but other conditions may still be possible.
While rare, certain medications or infections could influence antibody levels. Always inform your healthcare provider about any medications, supplements, or recent illnesses before the test.
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy