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24-Hour Urine Microalbumin-to-Creatinine Ratio

Published: August 9, 2026Updated: August 17, 2026

Measures urinary albumin relative to creatinine collected over 24 hours to assess how much albumin the kidneys are releasing.

Quick summary

["An elevated result may be an early sign of kidney damage, particularly in people with diabetes or high blood pressure."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
14958-3
Short code
Microalbumin/Creat 24h Ur
Synonyms
Microalbumin/Creat 24h Ur
Category
kidney
Sample
urine
Container
Sterile urine container
Units
N/A
Ref low
3.5
Ref high
5
Critical range
1.5 N/A – —
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
detection-limit-mg-l
CPT
82040
SNOMED
22383007
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

This test measures small amounts of albumin in urine compared with the amount of creatinine. The 24-hour collection provides a measure of albumin excretion over a full day, while creatinine helps account for differences in urine concentration.

Why might I need this test?

It may be used to screen for early kidney damage, especially in people with diabetes, high blood pressure, or other conditions that can affect the kidneys. It can also help monitor kidney function over time.

How is the test performed?

You collect all urine for 24 hours in the container provided by the laboratory. The urine is then analyzed to determine the amount of albumin relative to creatinine.

How do I prepare for the test?

Follow the laboratory's collection instructions, including the required start and end times. Do not leave urine in the container unrefrigerated for long periods, and tell the healthcare team if a collection is missed, spilled, or completed too quickly or slowly.

Reference range

Adult: 3.5-5.0 g/dLN/A

Specimen: urine

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

An elevated microalbumin-to-creatinine ratio can indicate that the kidneys are allowing more albumin than usual into the urine. This may be an early sign of kidney disease and can be associated with diabetes, high blood pressure, or other kidney-related conditions. Results should be interpreted by a healthcare professional and may be repeated to confirm an abnormal finding.

Short name

24-Hour Urine Microalbumin/Creatinine Ratio

Frequently asked questions

What does microalbumin mean?
Microalbumin is a small amount of albumin in urine, sometimes called moderately increased albuminuria. It may be found before other signs of kidney disease become apparent.
Why is creatinine included in the test?
Creatinine is used to adjust the albumin measurement for how concentrated the urine is. This makes the results easier to compare between samples.
How do I collect a 24-hour urine sample?
Use the supplied container and follow the laboratory's exact instructions for when to begin and finish the collection. All urine produced during that period should be included, and the healthcare team should be notified if the collection was incomplete.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy