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24-Hour Urine Microalbumin and Creatinine Panel

Published: August 9, 2026Updated: August 17, 2026

Measures urinary albumin and creatinine from a 24-hour urine collection to assess kidney filtration and detect early signs of kidney damage.

Quick summary

["This test can identify small amounts of albumin leaking into the urine, an early sign of kidney disease."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
58447-4
Short code
Microalbumin/creat Pnl 24H Ur
Synonyms
Microalbumin/creat Pnl 24H Ur
Category
kidney
Sample
urine
Container
Sterile urine container
Units
N/A
Ref low
3.5
Ref high
5
Critical range
1.5 N/A – —
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82040
SNOMED
22383007
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

This test measures the amount of albumin, a protein normally retained by the kidneys, and creatinine, a waste product, in urine collected for 24 hours. The results help assess kidney function and whether small amounts of protein are escaping into the urine.

Why might I need this test?

It may be ordered to screen for or monitor kidney disease, particularly in people with diabetes, high blood pressure, or other conditions that can affect the kidneys. It can also help evaluate changes in kidney function over time.

How is the test performed?

You collect all urine for exactly 24 hours, usually in a special container provided by the laboratory. The laboratory then measures albumin and creatinine and may calculate the urine albumin-to-creatinine ratio and total excretion over the collection period.

How do I prepare for the test?

Follow the laboratory's collection instructions and record the start and finish times. Avoid vigorous exercise shortly before and during the collection, do not change your usual fluid intake, and tell the laboratory if you recently had an illness, infection, or fever.

Reference range

Adult: 3.5-5.0 g/dLN/A

Specimen: urine

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

An increased amount of urine albumin or an elevated albumin-to-creatinine ratio may indicate that the kidneys are allowing excess protein to leak into the urine, which can be an early sign of kidney disease. Persistently abnormal results are usually interpreted along with blood creatinine, estimated glomerular filtration rate, blood pressure, and other clinical findings. Abnormal results do not identify the specific cause by themselves and may need repeat testing.

Short name

24-Hour Urine Microalbumin/Creatinine

Frequently asked questions

What is urine microalbumin?
Urine microalbumin is a small amount of albumin, a protein that the healthy kidneys normally keep in the blood. Increased urinary albumin can be an early sign of kidney damage.
Why is creatinine measured at the same time?
Creatinine is a muscle waste product filtered by the kidneys. Comparing it with urinary albumin accounts for differences in urine concentration and helps show whether albumin excretion is unusually high.
How do I collect a 24-hour urine sample?
Empty your bladder at the recorded start time, then collect every drop of urine for the next 24 hours in the designated container. At the end, urinate once more and include that urine; keep the container closed and refrigerate it if instructed.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy