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Microalbumin-to-Creatinine Ratio, Urine

Published: August 9, 2026Updated: August 17, 2026

This urine test measures small amounts of albumin relative to creatinine, helping assess kidney health and detect early signs of kidney damage.

Quick summary

["An elevated urine albumin-to-creatinine ratio may signal early kidney damage, especially in people with diabetes or high blood pressure."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
34535-5
Short code
Microalbumin/Creat ratio pnl Ur
Synonyms
Microalbumin/Creat ratio pnl Ur
Category
kidney
Sample
urine
Container
Sterile urine container
Units
N/A
Ref low
3.5
Ref high
5
Critical range
1.5 N/A – —
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82040
SNOMED
22383007
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

The urine albumin-to-creatinine ratio, also called UACR, measures a small amount of urine albumin relative to urine creatinine. Albumin is a protein that should normally be retained by the kidneys, while creatinine helps account for how concentrated the urine is.

Why might I need this test?

This test may be used to screen for or monitor kidney disease, particularly in people with diabetes, high blood pressure, or other conditions that can affect the kidneys. It can detect albumin leakage in the urine before noticeable symptoms develop.

How is the test performed?

You provide a urine sample, and the laboratory measures albumin and creatinine in it. A first-morning urine specimen may be requested because it is usually more concentrated, but collection instructions can vary by laboratory.

How do I prepare for the test?

Follow the laboratory's collection instructions and use the provided clean-catch container if directed. Tell your clinician about recent fever, vigorous exercise, urinary infection, or menstrual bleeding, as these can temporarily affect the result.

Reference range

Adult: 3.5-5.0 g/dLN/A

Specimen: urine

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

An elevated ratio may indicate that the kidneys are allowing more albumin to leak into the urine, which can be an early sign of kidney disease. This finding may also be associated with high blood pressure, diabetes, inflammation, or other kidney conditions and should be interpreted alongside other kidney tests. A single abnormal result does not always establish a diagnosis, so repeat testing or additional evaluation may be needed.

Short name

Urine albumin-to-creatinine ratio (UACR)

Frequently asked questions

Is this the same as a routine urinalysis?
No. A routine urinalysis may check for protein using a dipstick, while this test specifically quantifies small amounts of albumin relative to creatinine.
Does an elevated result mean I definitely have kidney disease?
Not necessarily. It can be an early warning sign, but temporary factors such as exercise, fever, or infection can also affect the result.
Do I need to collect a 24-hour urine sample?
Usually, no. This test is commonly performed on a spot urine sample, sometimes preferred as a first-morning specimen, but follow the specific instructions provided by the laboratory.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy