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MicroRNA Resistance-Associated Protein 1 (MRAP1) Mutation Screening in Plasma

Published: August 9, 2026Updated: August 16, 2026

This test checks for specific genetic changes in the MRAP1 gene, which may be linked to certain inherited conditions affecting metabolism or immune function. It uses a blood sample to identify mutations that could influence how your body functions at a molecular level.

Quick summary

["This screening helps identify potential genetic variations that may require further medical evaluation."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
92248-4
Short code
Micro resist mut AA change Islt/Spm
Synonyms
Micro resist mut AA change Islt/Spm
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
molgen
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have a family history of conditions like certain metabolic disorders, lysosomal storage diseases, or immune system abnormalities. It could also be part of prenatal testing or genetic counseling for individuals with suspected inherited genetic mutations.

What to Expect Before the Test

No special preparation is needed. You’ll have a small blood sample drawn from your arm, similar to other routine blood tests. The sample will be sent to a lab for genetic analysis.

What the Test Results Mean

Results will indicate whether specific mutations in the MRAP1 gene are present. If mutations are found, they may suggest an increased risk for certain genetic conditions. Your doctor will discuss these findings in the context of your medical history and family health.

Common Conditions Linked to MRAP1 Mutations

Mutations in MRAP1 are associated with rare genetic disorders, such as certain lysosomal storage diseases or metabolic disorders. These conditions may affect how your body breaks down certain substances, leading to health issues like organ damage or developmental delays.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

MRAP1 Mutation Screen

Frequently asked questions

What does a positive result mean?
A positive result means the test detected specific genetic changes (mutations) in the MRAP1 gene. These mutations may increase your risk for certain inherited conditions, but they don’t always cause symptoms. Your doctor will explain how these findings fit into your overall health and next steps.
Can this test be used for prenatal screening?
Yes, this test can be part of prenatal genetic testing if there’s a family history of MRAP1-related conditions. It may be offered during pregnancy to assess whether the fetus carries the same mutations as the parent, helping guide expectant parents’ decisions.
Are there any risks or side effects from this blood test?
The blood draw is generally safe but may cause mild discomfort or bruising at the site. Rarely, there could be a slight reaction to the needle, but serious complications are uncommon. Follow-up care is usually not needed unless your doctor identifies specific findings requiring further action.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy