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Serum or plasma mass concentration of immunoglobulin G (IgG) by immunoassay

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of Immunoglobulin G (IgG), a type of antibody in your blood. IgG helps protect your body from infections and is important for long-term immunity.

Quick summary

["IgG levels help doctors check for immune system health and response to vaccines or infections."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
2459-6
Short code
M-IgA Ser-mCnc
Synonyms
M-IgA Ser-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is Immunoglobulin G (IgG)?

IgG is the most common type of antibody in your blood. It plays a key role in fighting off infections and helping your body remember past illnesses, which helps prevent future infections. Antibodies like IgG are produced by your immune system to recognize and neutralize harmful substances, such as bacteria and viruses.

Why Might You Need This Test?

Your doctor may order an IgG test to evaluate your immune system function. This could be done if you have symptoms of a weakened immune system, such as frequent infections, unusual bruising, or unexplained fatigue. It may also be used to monitor immune responses after vaccination or to diagnose conditions like immunodeficiency disorders.

Common Reasons for Testing

Common reasons for this test include assessing immune function in people with recurrent infections, evaluating immune responses to vaccines, diagnosing conditions like HIV, checking for immune deficiencies, or monitoring diseases that affect the immune system.

What to Expect Before the Test

No special preparation is usually needed for this test. You may be asked to fast for a few hours before the blood draw if your lab requires it, but this is not always the case. Bring any medications or supplements you take regularly to your appointment.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

IgG Level

Frequently asked questions

How long does it take to get the results of this test?
Results for IgG tests are typically available within one to three business days, depending on your lab’s processing schedule. Your doctor will discuss the results with you during your follow-up visit.
Can low or high IgG levels be dangerous?
Low IgG levels may indicate a weakened immune system and could increase your risk of infections. High IgG levels alone are usually not dangerous but may be seen in chronic infections, autoimmune diseases, or certain immune responses. Your doctor will interpret results in the context of your overall health and symptoms.
Does this test help diagnose specific conditions?
Yes, IgG levels can help diagnose or monitor conditions like immunodeficiency disorders, HIV, certain autoimmune diseases, and immune system responses to infections or vaccines. However, additional tests may be needed for a full diagnosis.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy