Mass concentration of serum/plasma magnesium (total)
This test measures the total amount of magnesium in your blood serum or plasma, an essential mineral that plays a key role in muscle and nerve function, blood pressure regulation, and bone health.
["Your blood magnesium levels help ensure proper muscle and nerve function and support overall health."]
Key facts at a glance
- LOINC
- 2473-7
- Short code
- M-IgM Ser-mCnc
- Synonyms
- M-IgM Ser-mCnc
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 82784
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Your doctor may order this test if you have symptoms such as muscle cramps, weakness, twitching, numbness, or an irregular heartbeat. It is often used to check for problems related to kidney disease, diabetes, poor nutrition, or alcohol use, and to monitor treatment with medications such as diuretics that can affect magnesium levels.
Your healthcare provider may recommend this test if you have symptoms like muscle cramps, weakness, irregular heartbeat, or signs of low or high magnesium levels. It may also be part of routine testing for conditions like kidney disease, heart problems, or electrolyte imbalances.
In most cases, no special preparation is needed, but your doctor may ask you to stop taking certain supplements or medicines, such as antacids or laxatives that contain magnesium, before the blood draw. Tell your care team about all medications, vitamins, and herbal products you take. You can usually eat and drink normally unless you are told otherwise.
No special preparation is usually needed, but you may be asked to fast for a few hours before the blood draw if your test is part of a metabolic panel. Wear comfortable clothing and plan to rest for a short time afterward.
During the test, a health professional will clean your skin, wrap an elastic band around your upper arm, and draw a small sample of blood from a vein, usually in your arm or hand. You may feel a quick sting or pinch when the needle goes in. The sample is then sent to a laboratory, and the process usually takes only a few minutes.
A healthcare professional will draw blood from a vein in your arm. You may feel a slight pinch, but the procedure is quick. The blood sample is then sent to a lab for analysis.
Your results show how much magnesium is in your blood compared with the normal reference range. Levels that are too low or too high may point to issues with your kidneys, digestive system, or the medications you take. Your doctor will review your results along with your symptoms, medical history, and other tests before deciding on any next steps.
Results are typically reported in milligrams per deciliter (mg/dL). While reference ranges vary by lab, low levels may suggest conditions like kidney disease or malnutrition, while high levels could indicate kidney problems or certain medications.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Short name
Total Serum Magnesium
Frequently asked questions
Low magnesium levels can lead to muscle spasms, irregular heartbeat, or weakness, while high levels may cause nausea, confusion, or abnormal heart rhythms. Chronic imbalances can affect multiple body systems, so it’s important to discuss results with your provider.
A low magnesium level may indicate conditions like kidney disease, diarrhea, vomiting, or certain medications that deplete magnesium. It can also be linked to poor nutrition or metabolic disorders. Your provider will review your symptoms and other test results to determine the cause.
High magnesium levels can result from kidney problems (which can’t properly remove excess magnesium), certain medications, or severe dehydration. It may also be seen in conditions like Addison’s disease or overuse of antacids. Your provider will assess your overall health and other factors.
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy