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Milnacipran/Creatinine [Mass Ratio] in Urine

Published: August 9, 2026Updated: August 17, 2026

A calculated urine test that measures milnacipran relative to creatinine, helping account for differences in urine concentration.

Quick summary

["This test can help a clinician evaluate how much milnacipran is being excreted in the urine."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
87788-6
Short code
Milnacipran/Creat Ur Cfm
Synonyms
Milnacipran/Creat Ur Cfm
Category
kidney
Sample
urine
Container
Sterile urine container
Units
N/A
Critical range
0.5 N/A – —
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
confirm
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

This is a calculated urine test for milnacipran, a prescription medicine used to treat certain pain and anxiety conditions. It compares the amount of milnacipran with the amount of creatinine in the same urine sample.

Why might I need this test?

Your clinician may use this test to assess drug exposure, medication adherence, or how your body is handling milnacipran. Creatinine is included because urine concentration can vary with hydration and other factors.

How is the test performed?

A urine specimen is collected and tested for milnacipran and creatinine. The laboratory then calculates the amount of milnacipran relative to the amount of creatinine in that sample.

How do I prepare for the test?

Follow your clinician's collection instructions, including the timing and type of urine sample requested. Fasting is usually not required, and your clinician should be told when you last took milnacipran.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

A higher ratio may occur with recent dosing, concentrated urine, higher-than-expected drug exposure, or reduced drug clearance. A lower ratio may occur with dilute urine, lower drug exposure, reduced intake, or missed doses. Hydration, kidney function, sample timing, and the medication dose must be considered when interpreting the result.

Short name

Urinary Milnacipran/Creatinine Ratio

Frequently asked questions

What does the milnacipran-to-creatinine ratio show?
It shows the amount of milnacipran in the urine relative to creatinine. The ratio can help account for variation in how concentrated a urine sample is.
Is this the same as a routine urine creatinine test?
No. A routine urine creatinine test measures creatinine alone, while this test also measures milnacipran and calculates their ratio.
How is the result used by my clinician?
Your clinician will interpret it with your dose, timing of the last dose, kidney function, hydration, and symptoms. This result should not be used alone to change treatment.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy