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Mirtazapine concentration in plasma (quantitative)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of mirtazapine, a prescription antidepressant, in your blood plasma. It helps your healthcare provider assess drug levels to ensure proper dosing and monitor for potential side effects.

Quick summary

["This test helps confirm if your mirtazapine dose is working as intended and whether you may need adjustments."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
73260-2
Short code
Mirtazapine ind plt IgM SerPl Ql FC
Synonyms
Mirtazapine ind plt IgM SerPl Ql FC
Category
hematology
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
flow-cytometry
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order this test if you’re taking mirtazapine to check if your blood levels are within the recommended range. It’s especially useful for patients who haven’t responded well to the medication or are experiencing unusual side effects. Blood levels can vary based on how your body processes the drug, so monitoring helps optimize treatment.

What to Expect Before the Test

No special preparation is needed for this test. You’ll have a small needle inserted into your arm to draw a blood sample. It usually takes a few minutes, and you may feel a brief pinch. If you’re on blood thinners, let your doctor know before the test.

What to Expect During the Test

The blood sample will be sent to a lab for analysis. Results are typically available within 24 to 48 hours, depending on your healthcare provider’s lab processes. Your doctor will discuss the results with you.

Possible Results and Next Steps

If your mirtazapine levels are too low, your doctor may adjust your dose to improve effectiveness. If levels are too high, they may reduce the dose to avoid side effects like dizziness, weight gain, or increased heart rate. Always follow your doctor’s guidance based on the results.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Mirtazapine is a serotonin-norepinephrine reuptake inhibitor (SNRI) used to treat depression and anxiety. Blood levels help determine if the medication is working properly. Low levels may indicate insufficient dosing, while high levels could signal toxicity or improper metabolism. Regular monitoring is particularly important in patients with liver or kidney issues, as these organs play a key role in drug clearance.

Short name

Mirtazapine Level (Plasma)

Frequently asked questions

How long does it take to get the results of this test?
Results are usually available within 24 to 48 hours, but this can vary depending on your lab and healthcare provider’s processes. Your doctor will contact you once they have the results.
Can I eat or drink before this test?
You can eat and drink normally before this test, as no special fasting is required. However, if you’re on blood thinners or have other medical conditions, let your doctor know before the test.
What are the most common side effects of mirtazapine?
Common side effects of mirtazapine include drowsiness, weight gain, dry mouth, and increased appetite. Less common but serious side effects may include increased heart rate, dizziness, or unusual bleeding. If you experience severe side effects, contact your doctor immediately.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy