Mitochondrial Antibody Profile (Screening)
This test checks for antibodies that may indicate an autoimmune condition targeting your mitochondria, which are the energy-producing parts of your cells. It helps evaluate conditions like autoimmune hepatitis or other inflammatory disorders.
["This screening may help identify potential autoimmune-related health concerns."]
Key facts at a glance
- LOINC
- 63277-8
- Short code
- Mitochondria Ab Fld Ql IF
- Synonyms
- Mitochondria Ab Fld Ql IF
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- if
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
The test detects the presence of antibodies specific to mitochondrial proteins. These antibodies can be part of an immune response against your body’s own cells, often linked to certain liver or muscle disorders. The test may include multiple markers to assess different mitochondrial targets.
Why It Might Be Ordered
Your healthcare provider may recommend this test if you have symptoms like fatigue, unexplained liver issues, muscle weakness, or other signs of autoimmune disease. It can also be used as part of a broader evaluation for conditions like autoimmune hepatitis, myositis, or other connective tissue disorders.
Sample Collection and Preparation
A blood sample is typically collected from a vein in your arm. The blood is processed to separate the serum or plasma, which contains the antibodies being tested. This sample is then analyzed in a laboratory using immunoassay methods to detect the presence of mitochondrial antibodies.
What to Expect Before the Test
There are usually no special preparations needed for this test. You may be asked to fast for a few hours before the blood draw if your provider recommends it, but this is not always required. Avoid heavy exercise or strenuous activity on the day of the test.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Positive results for mitochondrial antibodies can suggest an autoimmune condition affecting organs like the liver, kidneys, or muscles. These antibodies may indicate inflammation or damage to these tissues. While not all positive results lead to a definitive diagnosis, they can guide further testing and treatment planning. Always discuss results with your healthcare provider to understand their implications for your specific situation.
Short name
Mitochondrial Antibody Screen
Frequently asked questions
What does a positive result mean?
Will I need further testing if my results are positive?
Can lifestyle changes help if I have mitochondrial antibodies?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy