Mitochondrial Antibody Profile (Screening)
This test checks for antibodies that may indicate an autoimmune condition targeting your body’s mitochondria, which are essential for energy production in cells.
["This screening helps identify possible autoimmune disorders affecting mitochondrial function."]
Key facts at a glance
- LOINC
- 57413-7
- Short code
- Mitochondria Ab Ser Ql IB
- Synonyms
- Mitochondria Ab Ser Ql IB
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- ib
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
The test detects the presence of antibodies (autoantibodies) that target mitochondrial proteins. These antibodies can be part of conditions like autoimmune hepatitis, systemic lupus erythematosus, or other inflammatory diseases. The screening may include multiple mitochondrial antigens to improve detection sensitivity.
Why It Might Be Ordered
Your healthcare provider may recommend this test if you have symptoms like fatigue, muscle weakness, liver issues, or unexplained inflammation. It’s also used in diagnosing conditions where mitochondrial involvement is suspected, such as certain autoimmune liver diseases.
What to Expect Before the Test
No special preparation is needed. Blood is drawn from a vein, usually in your arm. You may feel slight discomfort, but it’s a quick and common procedure.
What the Results Mean
Positive results suggest a higher likelihood of autoimmune activity targeting mitochondria, but further testing (like confirmatory assays) and clinical correlation are needed. Negative results mean no detectable antibodies in this screening, but other causes of symptoms should still be evaluated.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Elevated mitochondrial antibodies can signal autoimmune diseases affecting organs like the liver, kidneys, or joints. Early detection may help manage symptoms and prevent complications. However, results alone don’t diagnose a condition—your doctor will review them alongside symptoms and other tests.
Short name
Mitochondrial Antibody Screen
Frequently asked questions
What does a positive screening result imply?
Can lifestyle changes affect mitochondrial antibody levels?
How often should this test be repeated?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy