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Mitochondrial Antibody Profile (Qualitative) - Fluid

Published: August 9, 2026Updated: August 16, 2026

This test checks for antibodies that may indicate an autoimmune condition targeting mitochondria, which are essential energy-producing parts of cells.

Quick summary

["This screening helps identify possible autoimmune disorders affecting organ function."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
63278-6
Short code
Mitochondria Ab Titr Fld IF
Synonyms
Mitochondria Ab Titr Fld IF
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
if
CPT
86430
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your doctor may recommend this test if you have symptoms like fatigue, muscle weakness, joint pain, or unexplained organ issues (e.g., liver, kidney, or heart problems). It’s also used in cases of suspected autoimmune diseases like systemic lupus erythematosus (SLE) or other connective tissue disorders.

What to Expect Before the Test

No special preparation is needed. A blood sample will be drawn from a vein in your arm. You may feel a slight pinch, but it usually takes only a few minutes. If you’re on blood thinners, let your doctor know before testing.

What the Test Results Mean

Results are qualitative (positive or negative). A positive result suggests the presence of mitochondrial antibodies, which may warrant further evaluation for autoimmune conditions. False positives can occur, so follow-up testing may be needed.

Common Conditions Linked to Positive Results

Positive results are most commonly associated with autoimmune diseases like chronic active hepatitis, autoimmune polyendocrinopathy syndrome type 1 (APS-1), or other rare autoimmune disorders. These conditions can affect multiple organs.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test helps doctors diagnose or monitor autoimmune diseases affecting mitochondria. Early detection can guide treatment plans to manage symptoms and prevent organ damage. It’s particularly useful in cases where other tests are inconclusive or symptoms are atypical.

Short name

Mitochondrial Antibody Screen (Qualitative)

Frequently asked questions

What does a positive result mean for my health?
A positive result means your blood contains antibodies targeting mitochondria, which may signal an autoimmune response. This doesn’t confirm a specific diagnosis but may prompt further testing to explore conditions like autoimmune hepatitis or APS-1.
Will I need to repeat this test?
Yes, follow-up testing may be recommended to confirm or refine the diagnosis. Your doctor will determine if additional blood tests, imaging, or other evaluations are needed based on your symptoms and results.
Can lifestyle changes help if this test is positive?
While no single lifestyle change can reverse autoimmune activity, managing symptoms through a balanced diet, stress reduction, and avoiding triggers (like certain medications or infections) may support overall health. Always work with your healthcare team for personalized advice.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy