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Mitochondrial Antibody Profile (Screen) – Serum

Published: August 9, 2026Updated: August 16, 2026

This test checks for antibodies against mitochondrial proteins, which may be linked to certain autoimmune conditions affecting the liver, kidneys, or other organs.

Quick summary

["A screen for mitochondrial antibodies that could signal autoimmune disorders requiring further evaluation."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
82840-0
Short code
Mitochondria IgG Ser Ql IF
Synonyms
Mitochondria IgG Ser Ql IF
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
if
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test detects specific proteins found in mitochondria—the energy-producing centers of cells. If your immune system mistakenly targets these proteins, it may indicate an autoimmune response, such as those seen in conditions like autoimmune hepatitis or certain kidney diseases.

Why It Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like fatigue, unexplained liver issues, joint pain, or kidney problems, especially if other tests haven’t identified a cause.

What to Expect Before the Test

No special preparation is needed. You’ll provide a blood sample, usually drawn from your arm. The process takes a few minutes, and you can resume normal activities afterward.

What the Results Mean

Positive results suggest a higher likelihood of an autoimmune condition affecting mitochondria, prompting further testing (like confirmatory antibody assays) or monitoring. Negative results mean no detectable antibodies were found in this sample.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Mitochondrial Antibody Screen

Frequently asked questions

How long does it take to get results?
Results are typically available within 1–3 business days, depending on lab processing times. Follow-up instructions from your healthcare provider will determine next steps.
Can I eat or drink before this test?
No special diet or fasting is required. You can eat and drink normally before your blood draw.
What if my results are positive?
A positive result may mean further testing (such as confirmatory antibody assays or liver/kidney function tests) is needed to explore potential autoimmune conditions. Your doctor will discuss next steps based on your symptoms and overall health.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy