Skip to content

Mitochondrial Antigen Antibody Profile (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures antibodies against mitochondrial proteins, often used to help diagnose conditions like autoimmune hepatitis or other liver-related disorders.

Quick summary

["Helps identify autoimmune liver diseases by detecting unusual immune responses."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
63282-8
Short code
Mitochondria M2 Ab CSF Ql IA
Synonyms
Mitochondria M2 Ab CSF Ql IA
Category
chemistry
Sample
csf
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your doctor may recommend this test if you have symptoms like unexplained fatigue, abdominal pain, jaundice (yellowing of skin/eyes), or liver enzyme abnormalities. It can also be used to monitor autoimmune conditions affecting the liver or other organs.

What to Expect Before the Test

No special preparation is typically needed. You may have a blood sample drawn from a vein in your arm. If you’re on blood thinners, let your doctor know before the test.

What the Results Mean

Positive results suggest an immune response targeting mitochondrial proteins, which may indicate conditions like autoimmune hepatitis or other mitochondrial disorders. Results alone don’t diagnose a specific condition but guide further testing.

Common Conditions Linked to Positive Results

Positive results are most commonly associated with autoimmune liver diseases (e.g., primary biliary cholangitis) or other rare mitochondrial disorders. Your doctor will interpret results in the context of your symptoms and other test findings.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Mitochondrial Antibody Test

Frequently asked questions

What symptoms might lead to this test?
Symptoms such as persistent fatigue, unexplained weight loss, jaundice, dark urine, pale stools, or elevated liver enzymes (e.g., bilirubin, ALT) may prompt this test. It’s also used in research or rare cases of suspected mitochondrial disorders.
Can this test replace other liver function tests?
No. This test is one tool among many. Your doctor may order it alongside other tests (e.g., liver enzymes, viral hepatitis markers) to narrow down a diagnosis.
How long does it take to get results?
Results are usually available within 1–3 business days, depending on your lab’s processing time.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy