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Mitochondrial Antigen Antibody Profile (Serum)

Published: August 9, 2026Updated: August 16, 2026

This test measures antibodies against mitochondrial proteins, often used to help diagnose conditions like autoimmune hepatitis or other liver-related disorders.

Quick summary

["This blood test checks for immune system activity against mitochondria, which may signal liver or other autoimmune issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
111022-0
Short code
Mitochondria M2 Ab Msmt Ser
Synonyms
Mitochondria M2 Ab Msmt Ser
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Doctors may order this test if you have symptoms like unexplained fatigue, liver problems (such as jaundice or elevated liver enzymes), or signs of an autoimmune condition. It helps identify whether your immune system is attacking mitochondria, which can be linked to certain liver diseases or other systemic disorders.

What to Expect Before the Test

No special preparation is needed, but you may fast for 8–12 hours before drawing blood if instructed by your healthcare provider. Wear a comfortable shirt for easy access to your arm.

What the Test Involves

A healthcare professional will insert a needle into a vein in your arm to collect a small amount of blood. The process usually takes a few minutes and may cause mild discomfort.

What the Results Mean

Positive results for mitochondrial antibodies may indicate an autoimmune condition affecting the liver or other organs. Your doctor will interpret results in the context of your symptoms, medical history, and other tests.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated mitochondrial antibodies often signal autoimmune hepatitis or other mitochondrial disorders, which can cause chronic liver inflammation, fatigue, or muscle weakness. Early detection helps guide treatment, such as medications to reduce immune activity or manage symptoms.

Short name

Mitochondrial Antibody Panel

Frequently asked questions

What does a positive result mean?
A positive result suggests your immune system may be attacking mitochondrial components, which could be linked to autoimmune liver disease or other conditions. Your doctor will discuss next steps, such as further testing or treatment options.
Can this test be done at home?
No, this test requires a blood draw by a healthcare professional. Some labs may offer at-home blood collection services, but results must be analyzed by a lab and reviewed by your doctor.
How long does it take to get results?
Results are typically available within 1–3 business days, depending on your lab’s processing time. Your doctor will explain the findings during your follow-up visit.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy