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Mitochondrial Antibody Profile (Screening)

Published: August 9, 2026Updated: August 16, 2026

This test measures antibodies that may indicate an autoimmune condition targeting mitochondria in your body’s cells. It helps assess potential autoimmune disorders affecting organs like the liver, kidneys, or heart.

Quick summary

["This screening may help identify conditions linked to mitochondrial antibodies, guiding further medical evaluation."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
56735-4
Short code
Mitochondria M2 Ab Ser Ql IB
Synonyms
Mitochondria M2 Ab Ser Ql IB
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ib
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may order this test if you have symptoms like fatigue, muscle weakness, or unexplained organ dysfunction. It’s also used in diagnosing conditions such as autoimmune hepatitis or other mitochondrial disorders.

What to Expect During the Test

A blood sample is taken from a vein in your arm. You may feel a slight pinch, but it usually doesn’t cause discomfort. The sample is sent to a lab for analysis.

What the Results Mean

Positive results suggest the presence of mitochondrial antibodies, which may warrant further testing or a referral to a specialist. Negative results mean no detectable antibodies were found in this sample.

Common Conditions Linked to This Test

Conditions like autoimmune hepatitis, chronic active hepatitis, or other autoimmune disorders involving mitochondrial dysfunction may be associated with positive results.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Mitochondrial Antibody Screen

Frequently asked questions

What does a positive result mean?
A positive result indicates the presence of mitochondrial antibodies, which may suggest an autoimmune condition affecting organs. Your doctor will discuss next steps, which could include additional tests or specialist evaluation.
How often should I get this test?
Your doctor will determine the frequency based on your symptoms, medical history, and test results. Follow-up may be needed if initial results are positive or if symptoms persist.
Can lifestyle changes help if this test is positive?
While lifestyle changes like a balanced diet, stress management, and avoiding triggers (e.g., certain medications) may support overall health, they won’t replace medical treatment. Work closely with your healthcare provider to address underlying conditions.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy