Mitochondrial Antibody Profile (Serum) – Immunoassay Panel

What This Test Measures

The test detects specific antibodies (immunoglobulins) that target mitochondrial components in your blood. These antibodies can be part of an autoimmune response, where your immune system mistakenly attacks healthy cells. The panel typically includes tests for common mitochondrial antigens, such as those associated with autoimmune hepatitis or other systemic autoimmune diseases.

Why It’s Ordered

Your healthcare provider may order this test if you have symptoms like fatigue, liver issues (e.g., jaundice, abdominal pain), kidney problems, or other signs of autoimmune disease. It may also be used to monitor treatment progress or confirm a diagnosis in suspected cases.

Sample Collection and Preparation

A blood sample is drawn from a vein in your arm. The serum portion (liquid part after clotting) is separated and sent to the lab for testing. This test is typically done on fresh or stored serum samples, often analyzed using immunoassay methods to detect antibody presence.

Common Conditions Linked to Positive Results

Positive results may suggest autoimmune conditions like autoimmune hepatitis, systemic lupus erythematosus (SLE), or other mitochondrial-related autoimmune disorders. However, false positives can occur, so results are often interpreted alongside clinical findings and other tests.