Mitochondrial Antigen Antibody Profile (Screening)
This test checks for antibodies against mitochondrial proteins, which may indicate conditions like autoimmune hepatitis or other liver-related disorders.
["This screening helps identify potential autoimmune liver issues by detecting unusual immune responses."]
Key facts at a glance
- LOINC
- 56632-3
- Short code
- Mitochondria M2 IgG Titr Ser IF
- Synonyms
- Mitochondria M2 IgG Titr Ser IF
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 8
- Ref high
- 61
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- if
- CPT
- 82977
- SNOMED
- 3110003
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Might Be Ordered
Your healthcare provider may recommend this test if you have symptoms like unexplained fatigue, jaundice (yellowing of skin/eyes), abdominal pain, or liver enzyme abnormalities detected on other tests. It’s also used in cases where autoimmune liver diseases are suspected but not clearly diagnosed.
What to Expect Before the Test
No special preparation is needed. A blood sample will be drawn from a vein, typically in your arm. You may feel a slight pinch, but it usually takes a few minutes to complete.
What the Test Measures
The test detects the presence of antibodies targeting mitochondrial proteins, which are involved in energy production in cells. These antibodies can signal an immune system response against healthy liver cells.
Possible Results and Next Steps
A positive result suggests a higher likelihood of autoimmune liver disease, prompting further evaluation (such as liver function tests, biopsy, or additional antibody testing). A negative result means no obvious antibodies were found, but other causes of symptoms should still be investigated.
Reference range
Adult males: 8-61 U/L; Adult females: 5-36 U/LN/A
No special preparation required. Avoid fatty meals before the test if possible.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
Mitochondrial Antibody Test (Screen)
Frequently asked questions
What does a positive result mean?
How long does it take to get results?
Can lifestyle changes help if this test is positive?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy