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Fibrinogen (Serum) Mass Concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of fibrinogen, a protein in your blood that plays a key role in blood clotting. Low levels may increase bleeding risk, while high levels could suggest conditions like liver disease or inflammation.

Quick summary

["Fibrinogen helps control bleeding and supports blood clotting; levels can signal health risks or conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
71772-8
Short code
Mitogen IGNF Bld-aCnc
Synonyms
Mitogen IGNF Bld-aCnc
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms of bleeding disorders, signs of liver disease, or if you’re scheduled for surgery or a procedure that requires careful blood clotting monitoring. It can also help diagnose or monitor conditions like disseminated intravascular coagulation (DIC) or certain inflammatory diseases.

What to Expect Before the Test

No special preparation is needed for this blood test. You may fast for 8–12 hours before the draw if instructed by your provider, but confirm with them first. Wear a comfortable shirt with sleeves rolled up, as you’ll need to expose an arm for the blood draw.

What Happens During the Test

A healthcare professional will clean a vein in your arm with an antiseptic and insert a small needle to collect blood. You may feel a brief pinch, but the process usually takes just a few minutes. The blood sample is then sent to the lab for analysis.

What the Results Mean

Results are reported as a mass concentration (typically in grams per liter). Your provider will compare these results to your individual reference range and clinical picture to determine if further action is needed. Very low or very high levels may require additional testing or treatment.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Fibrinogen Level

Frequently asked questions

What could low fibrinogen levels indicate?
Low fibrinogen can signal conditions like liver disease (where production is impaired), severe infections, or blood loss. It may also appear in people with certain cancers or autoimmune disorders. Always discuss symptoms with your provider, as other factors can influence results.
What could high fibrinogen levels indicate?
Elevated fibrinogen is often seen in inflammatory conditions (e.g., rheumatoid arthritis), pregnancy, or chronic infections. It can also be a normal response to stress or trauma. High levels alone may not need treatment unless they’re associated with symptoms like swelling or clotting issues.
How often should I get this test?
Your provider will determine how often to check your fibrinogen based on your health status, symptoms, and treatment plan. Regular monitoring may be needed if you have ongoing conditions like liver disease or inflammatory disorders.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy