Serum/plasma concentration of lipoprotein(a) [Lp(a)]

What Is Lipoprotein(a)?

Lipoprotein(a), or Lp(a), is a unique lipoprotein particle that combines cholesterol with a protein called apolipoprotein(a). While it shares similarities with LDL (low-density lipoprotein), Lp(a) is distinct and may play a role in artery hardening and blood clot formation. High levels are often inherited but can also be influenced by lifestyle factors.

Why Might You Need This Test?

Your healthcare provider may order this test if you have a family history of heart disease, stroke, or blood clots, or if you have conditions like high cholesterol, hypertension, or diabetes. It’s also used to assess risk in certain genetic testing scenarios or before procedures involving blood vessel intervention.

How Is the Test Performed?

A blood sample is drawn from a vein, typically in your arm. The sample is then sent to a lab for analysis using an immunoassay method to measure the precise concentration of Lp(a) in your serum or plasma.

What Do Results Mean?

Results are reported as a numerical value representing the concentration of Lp(a) in milligrams per deciliter (mg/dL). While there are no universally accepted reference ranges for Lp(a) due to its genetic variation, higher levels are generally associated with increased cardiovascular risk.