Lipoprotein(a) [Lp(a)] Serum Concentration by Immunoassay

What Is Lipoprotein(a)?

Lipoprotein(a) is a unique lipoprotein particle that combines cholesterol with a protein called apolipoprotein(a). While it shares similarities with LDL (low-density lipoprotein), it behaves differently in the body and is associated with increased risk of blood clots and heart disease. High levels may contribute to arterial plaque buildup over time.

Why Might You Need This Test?

Your healthcare provider may order this test if you have a family history of heart disease, stroke, or early-onset vascular issues, or if you’re at higher risk due to other health conditions like diabetes or high blood pressure. It may also be used in certain genetic testing or risk stratification scenarios.

How Is the Test Performed?

A blood sample is drawn from a vein, typically in your arm. The sample is sent to a lab where it’s analyzed using an immunoassay method to detect and quantify lipoprotein(a) levels.

What Does the Test Result Mean?

Results are reported in milligrams per deciliter (mg/dL) or micrograms per milliliter (µg/mL). While there are no universally accepted reference ranges for lipoprotein(a) due to variability among individuals, higher levels may indicate an increased risk for cardiovascular events. Your doctor will interpret results in the context of your overall health and medical history.