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Serum or Plasma Immunoassay for Anti-Mycoplasma pneumoniae Antibodies (Qualitative or Quantitative)

Published: August 9, 2026Updated: August 16, 2026

This test measures antibodies in your blood that your immune system produces in response to *Mycoplasma pneumoniae*, a common bacterial cause of respiratory infections like pneumonia and bronchitis.

Quick summary

["Helps diagnose infections caused by *Mycoplasma pneumoniae* when symptoms like cough or fever persist."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
72870-9
Short code
M leprae rpoB RIF res mut Islt/Spm Ql
Synonyms
M leprae rpoB RIF res mut Islt/Spm Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
molgen
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test detects antibodies (IgG or IgM) produced by your body after exposure to *Mycoplasma pneumoniae*. Antibodies appear after infection or vaccination and can linger for months or years. This test is often used to confirm a diagnosis when other tests (like culture or PCR) are inconclusive or unavailable.

When You Might Need This Test

Your healthcare provider may recommend this test if you have symptoms like persistent cough, fever, or chest pain that suggest a respiratory infection, especially if tests for other common causes (like viruses or other bacteria) have been negative.

How the Test Works

Blood is drawn and sent to a lab where it is tested using an immunoassay method. This method detects specific antibodies in your serum or plasma that bind to *Mycoplasma pneumoniae* antigens, indicating past or current infection.

What to Expect Before the Test

No special preparation is needed. You may eat and drink normally on the day of the test, but inform your provider if you are on blood-thinning medications or have bleeding disorders, as this may affect blood collection.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Positive results suggest past or current infection with *Mycoplasma pneumoniae*. High antibody levels may indicate recent exposure or active infection, particularly in patients with atypical symptoms. However, false positives can occur, especially in people with other infections or autoimmune conditions. This test is often used alongside clinical findings and other diagnostic tools to guide treatment decisions.

Short name

Mycoplasma pneumoniae Antibody Test

Frequently asked questions

How long does it take to get results?
Results are typically available within 1 to 3 business days, depending on your lab’s processing schedule. Your healthcare provider will discuss the results with you during your follow-up visit.
Can this test be used to diagnose *Mycoplasma pneumoniae* infection right away?
No, this test measures antibodies, not the live bacteria. It’s most useful for confirming a diagnosis when symptoms persist or other tests are inconclusive. Your provider may also order a PCR test or culture for immediate detection of the bacteria.
What if my test results are positive but I don’t have symptoms?
A positive result could mean you had an infection in the past, or you may have been exposed to *Mycoplasma pneumoniae* without developing symptoms. Your provider will assess your medical history and symptoms to determine if further testing or treatment is needed.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy