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Organic Acid Profile (Metabolic Screening)

Published: August 9, 2026Updated: August 16, 2026

This test measures the levels of specific organic acids in your blood or urine, helping identify metabolic disorders.

Quick summary

["Assists in diagnosing conditions linked to abnormal acid metabolism."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
97625-8
Short code
M. morganii DNA Snv Ql NAA+n-prb
Synonyms
M. morganii DNA Snv Ql NAA+n-prb
Category
chemistry
Sample
fluid
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
non-probe-amp-tar
Specimen volume
2-5 mL
Stability
Room temperature: 2h, Refrigerated: 24h
Hemolysis max
300
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like frequent vomiting, unusual smells (e.g., sweaty feet or fruity breath), developmental delays, or a family history of metabolic disorders. It’s also used in newborn screening for certain inherited conditions.

What to Expect Before the Test

For blood tests, you’ll typically have a small sample drawn from a vein. For urine tests, you may need to collect a sample at home or in a lab. Follow any fasting instructions your provider gives you, as some tests require an empty stomach.

What the Test Results Mean

Abnormal results may indicate metabolic imbalances, such as mitochondrial disorders, organic acidemias, or other genetic conditions. Your provider will discuss findings with you and may recommend further testing or treatment plans.

Common Conditions Linked to This Test

This test can help detect conditions like methylmalonic acidemia, propionic acidemia, or multiple carboxylase deficiencies, which affect how your body breaks down certain nutrients.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Organic acid tests play a critical role in diagnosing rare but serious metabolic disorders early. Early detection can improve long-term outcomes and guide targeted therapies, including dietary modifications or enzyme replacement.

Short name

Organic Acid Test

Frequently asked questions

What triggers this test?
Symptoms such as unexplained vomiting, unusual body odors, developmental delays, or a family history of metabolic diseases often prompt this test.
How long does it take to get results?
Results may take several days to a couple of weeks, depending on lab processing and follow-up needs. Your provider will contact you once they’re ready for discussion.
Can I eat or drink before the test?
Follow your provider’s instructions—some tests require fasting, while others may allow water or specific diets. Always confirm with them before the procedure.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy