Skip to content

Organic Acid Profile (Metabolic Screening) via Mass Spectrometry

Published: August 9, 2026Updated: August 16, 2026

This test measures the levels of specific organic acids in your body, which can help identify metabolic disorders.

Quick summary

["Detecting unusual acid buildup may reveal conditions like mitochondrial diseases or inborn errors of metabolism."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
105667-0
Short code
M. morganii DNA Spec Ql NAA+probe
Synonyms
M. morganii DNA Spec Ql NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like unexplained vomiting, developmental delays, or neurological issues, or if you have a family history of metabolic disorders.

What to Expect Before the Test

No special preparation is needed. You may provide a sample of urine collected over a 24-hour period, depending on the specific acids being tested.

What the Results Mean

Abnormal levels of certain organic acids can indicate metabolic disorders. Elevated levels of specific acids may suggest conditions like methylmalonic acidemia or propionic acidemia.

Common Conditions Linked to Organic Acid Test Results

High levels of certain organic acids are often linked to inherited metabolic disorders. These conditions can affect how your body breaks down food for energy.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Organic acid tests are crucial for diagnosing metabolic disorders early, which can help manage symptoms and improve quality of life. Early intervention can prevent complications and support long-term health.

Short name

Organic Acid Test

Frequently asked questions

What causes abnormal organic acid levels?
Abnormal organic acid levels are most commonly due to genetic mutations that disrupt normal metabolism. These mutations can prevent your body from breaking down certain foods or waste products properly.
How often should I get this test?
The frequency depends on your health status and any diagnosed metabolic condition. Your healthcare provider will determine if follow-up tests are needed based on your results and symptoms.
Can diet changes affect organic acid test results?
Yes, diet can influence organic acid levels. Certain foods or dietary restrictions may be recommended by your doctor to help manage metabolic conditions detected by this test.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy