Skip to content

Serum or plasma concentration of myoglobin

Published: August 9, 2026Updated: August 16, 2026

Myoglobin is a protein found in muscle cells that helps release oxygen. Elevated levels may suggest muscle damage or other conditions.

Quick summary

["This test helps identify possible muscle injury or other health concerns affecting muscle proteins."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
31902-0
Short code
M myc my sc Ag Spec Ql
Synonyms
M myc my sc Ag Spec Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Might Myoglobin Levels Be Tested?

Your doctor may order this test if you have symptoms like muscle pain, weakness, or unexplained fatigue, especially after trauma, exercise, or conditions like rhabdomyolysis (severe muscle breakdown). It can also be checked in cases of suspected acute kidney injury, as myoglobin can damage kidney cells when present in high amounts.

What Does a High or Low Myoglobin Level Mean?

High levels may indicate recent muscle injury (e.g., from a crash, fall, or intense exercise), certain infections, or conditions like myoglobinuria (dark urine due to myoglobin). Low levels are less commonly significant unless related to muscle disorders or certain medications.

How Is This Test Performed?

A blood sample is drawn from a vein, usually in your arm. The sample is sent to a lab where it is analyzed using an immunoassay or similar method to measure myoglobin concentration.

What Are Common Causes of Abnormal Results?

Common causes of elevated myoglobin include muscle trauma, severe exercise, alcohol abuse, or certain medications. Rarely, genetic muscle disorders or metabolic disorders may also affect levels.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: When Myoglobin Levels Matter

Short name

Myoglobin Level

Frequently asked questions

What are the normal reference ranges for myoglobin?
Reference ranges vary by lab and may not be widely standardized. Your doctor will interpret results in the context of your symptoms and medical history. High levels can signal kidney risk, so prompt follow-up may be needed.
How soon after an injury or event should I expect results?
Results may take 1–3 days, depending on lab processing. Your doctor will guide you on timing based on your situation.
Can lifestyle changes affect myoglobin levels?
Yes—avoiding excessive exercise, managing muscle stress, and staying hydrated may help prevent muscle damage that could raise myoglobin levels. Always discuss lifestyle changes with your healthcare provider.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy