Serum or Plasma Creatinine Concentration (Mass Concentration)

Why This Test Matters

Your kidneys normally filter waste products, including creatinine, from your blood. High levels of creatinine can indicate poor kidney function or damage, while low levels might suggest overhydration or other conditions. This test is often used alongside other kidney function tests to monitor kidney health, especially in people with diabetes, high blood pressure, or a history of kidney disease.

What to Expect Before the Test

No special preparation is needed for this test. You may have a small needle inserted into a vein (usually in your arm) to draw blood. If you’re on a blood thinner, let your healthcare provider know before the test.

What the Results Mean

Results are compared to a general reference range, but individual ranges can vary based on age, sex, and overall health. High creatinine levels may signal kidney problems, while very low levels could be due to dehydration or other factors. Your doctor will interpret results in the context of your medical history and other tests.

Common Causes of Abnormal Results

High creatinine levels can result from kidney disease, dehydration, severe muscle injury, or conditions that reduce blood flow to the kidneys. Low levels may occur with overhydration, certain medications, or liver disease. Always discuss any concerns with your healthcare provider.