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Serum/plasma concentration of total bilirubin

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of bilirubin in your blood, a yellow pigment produced when red blood cells break down. It helps assess liver function and bile flow.

Quick summary

["A bilirubin test checks for liver or bile duct issues and red blood cell health."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
50397-9
Short code
Mol dx interp Bld/T Ql
Synonyms
Mol dx interp Bld/T Ql
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
molgen
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Matters

Your liver normally processes bilirubin, which comes from the breakdown of old red blood cells. If your liver isn’t working well, bilirubin can build up in your blood, leading to jaundice (yellowing of skin or eyes). This test helps doctors identify problems like liver disease, gallbladder issues, or hemolytic anemia.

What to Expect Before the Test

No special preparation is needed for this test. You may have a blood draw from a vein in your arm, or if plasma is used, a small tube may be inserted into your vein. The process takes a few minutes, and you can resume normal activities afterward.

Common Causes of Abnormal Results

High bilirubin levels may indicate liver disease, blockages in the bile ducts, or conditions that cause red blood cells to break down too quickly. Low levels are less common but could suggest liver disease or certain medications.

What Your Results Mean

Results are usually reported in milligrams per deciliter (mg/dL). If your bilirubin is higher than expected, your doctor may order additional tests to find the cause. If it’s lower, they may investigate potential medications or conditions affecting liver function.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Total bilirubin

Frequently asked questions

What questions might I have about this test?
This test is often used alongside other liver function tests (like ALT or AST) to diagnose conditions like hepatitis, cirrhosis, or bile duct obstructions. If you have symptoms like fatigue, dark urine, or pale stools, mention them to your doctor.
Will fasting affect this test?
No, fasting is not required for bilirubin testing. However, if you’re taking medications that affect liver function, let your doctor know before the test.
How long will it take to get my results?
Results are typically available within 1–3 business days, depending on your lab. Your doctor will discuss them with you during your follow-up visit.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy