Molecular Resistance Testing by Sequencing (Plasma/Serum)

What This Test Measures

This test examines specific genes (such as those in bacteria or viruses) that may contribute to resistance against common antibiotics. By identifying these genetic markers, healthcare providers can tailor treatment plans to target the most effective drugs for your infection.

Why It’s Done

Doctors may order this test if you have a bacterial or viral infection that doesn’t respond to standard treatments, or if you’re at higher risk of antibiotic-resistant infections (e.g., frequent infections, hospital stays, or immune conditions). It helps prevent unnecessary antibiotic use and reduces the spread of resistant bacteria.

Sample Collection and Preparation

A blood sample (plasma or serum) is collected during a routine venipuncture. The sample is then processed in a lab to extract genetic material (DNA/RNA) for sequencing. Results are generated based on the presence of resistance-associated genes.

How Results Are Interpreted

Results show whether specific resistance genes are present in the pathogen causing your infection. If resistance genes are detected, doctors will adjust treatment to use antibiotics that are more likely to work effectively.