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Monocyte count in whole blood (automated cell differential)

Published: August 9, 2026Updated: August 16, 2026

This test measures the number of monocytes, a type of white blood cell, in your blood. Monocytes help fight infections and remove dead cells or debris.

Quick summary

["Monocytes are part of your immune system and help protect your body from illness."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
742-7
Short code
Monocytes # Bld Auto
Synonyms
Monocytes # Bld Auto
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
automated-count
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why is this test done?

Your healthcare provider may order a monocyte count to check for infections, inflammation, or other conditions that affect your immune system. It can also help diagnose or monitor certain blood disorders, autoimmune diseases, or reactions to treatments like chemotherapy.

What does a high or low monocyte count mean?

Elevated monocyte levels may suggest chronic infections, inflammation, or certain cancers. Low monocyte counts could indicate immune deficiencies, bone marrow disorders, or severe infections.

How is this test performed?

A small sample of your blood is drawn from a vein, usually in your arm. The blood is then analyzed automatically in a lab to count monocytes among other white blood cells.

What should I expect before or after the test?

You may feel slight discomfort at the injection site, but the procedure takes only a few minutes. Avoid strenuous activity for a short time afterward to prevent bruising.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Monocyte blood count

Frequently asked questions

What does a normal monocyte count mean for my health?
A normal range doesn’t guarantee your health is perfect, but it suggests your immune system’s monocyte activity is within typical limits. Always discuss results with your provider.
Can lifestyle changes affect monocyte counts?
Diet, exercise, and stress levels may indirectly influence immune function, but direct effects on monocyte counts are less clear. Focus on overall health habits.
How often should I get this test?
Your provider will determine frequency based on your medical needs, symptoms, or ongoing treatment. Regular monitoring may be needed if you have chronic conditions.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy