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Monocytesdock8monocytesnfrbldfc

Published: August 9, 2026Updated: August 17, 2026

This test measures the amount of DOCK8 protein in specific white blood cells called monocytes using flow cytometry technology.

Quick summary

{"The test measures DOCK8 protein levels in monocytes (CD14+ cells)","A blood sample is collected and analyzed in a laboratory","DOCK8 helps immune cells function properly","Results help doctors understand immune system health","The test uses flow cytometry to analyze cell markers"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
96419-7
Short code
DOCK8+ Mono
Synonyms
Monocytes DOCK8+/Monocytes NFr Bld FC
Category
cardiac
Sample
whole-blood
Container
EDTA purple-top tube (K2-EDTA)
Units
N/A
Ref low
85
Ref high
95
Critical range
— – 10000 N/A
Fasting
false
Population
adult
Sex
all
Age range
0–100 years
Method
flow-cytometry
CPT
88188
SNOMED
122598009
Specimen volume
2-3 mL of whole blood minimum; 5 mL preferred for optimal analysis
Stability
Room temperature (20-25°C): 24-48 hours. Refrigerated (2-8°C): up to 72 hours. Do not freeze. Ship at ambient temperature or refrigerated. Protect from extreme temperatures and direct sunlight.
Hemolysis max
50
Lipemia max
100
Icterus max
20
TAT
48–96 hours
Order
routine

What is this test?

This test measures the amount of DOCK8 protein in monocytes. Monocytes are a type of white blood cell that help your body fight infections and are part of your immune system. DOCK8 is a special protein that helps these immune cells work properly. The test uses flow cytometry, which is a laboratory technique that can identify and count different types of cells based on specific markers on their surface.

How is the test done?

A healthcare provider will draw a small sample of blood from your arm. This blood sample is then sent to a laboratory where special machines analyze the cells. The test looks at monocytes (identified by CD14 marker) and measures how much DOCK8 protein they contain. The results are expressed as a ratio comparing DOCK8-positive cells to total monocytes.

Why might I need this test?

Your doctor may order this test to check how your immune system is working. It can help diagnose or monitor conditions that affect the immune system. The test may also be used to understand certain heart-related conditions, as immune cells can play a role in cardiovascular health.

Reference range

Reference range: 85-95% of CD3-CD14+CD45+ cells express DOCK8. Reference values may vary by laboratory methodology and instrument. Clinical correlation recommended.N/A

Specimen: whole-blood

No special preparation required. Patient does not need to fast. Inform the laboratory of any recent infections, immunosuppressive therapy, or bone marrow transplantation as these may affect results.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Frequently asked questions

Do I need to fast before this test?
Typically, no fasting is required for this blood test. However, always follow your doctor's specific instructions.
How long does it take to get results?
Results are usually available within a few days to a week, as flow cytometry testing requires specialized laboratory processing.
Are there any risks from this test?
The risks are minimal and similar to routine blood tests, including slight bruising or soreness at the needle site.
What do the results mean?
Your doctor will interpret the results based on your overall health and other test results. Abnormal levels of DOCK8 in monocytes may require further investigation.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy