Skip to content

Monocyte Count (Peripheral Blood)

Published: August 9, 2026Updated: August 16, 2026

This test measures the number of monocytes, a type of white blood cell that helps fight infections and inflammation. Monocytes are part of your immune system and play a role in responding to chronic illnesses.

Quick summary

["Monocytes help protect your body from long-term infections and inflammation."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
5905-5
Short code
Monocytes NFr Bld Auto
Synonyms
Monocytes NFr Bld Auto
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
automated-count
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may order a monocyte count to evaluate your immune system function, check for signs of infection, inflammation, or blood disorders like leukemia. It can also help monitor conditions such as autoimmune diseases or chronic infections.

What to Expect Before the Test

You’ll typically have a small needle inserted into your arm or hand to draw a blood sample. This is usually quick and painless. Avoid strenuous activity or eating heavy meals 24 hours before the test if instructed.

What the Results Mean

Results are usually reported as the number of monocytes per microliter (µL) of blood. High or low counts can signal underlying health issues, but your provider will interpret results in the context of your overall health and symptoms.

Common Conditions Monitored

Monocyte counts are monitored in conditions like chronic inflammation, certain infections, or blood cancers. Elevated levels may indicate conditions like tuberculosis or certain cancers, while low levels could suggest immune deficiencies or other disorders.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Monocyte Count

Frequently asked questions

How often will I need this test?
The frequency depends on your health condition and provider’s recommendations. Some people may need this test monthly, quarterly, or only when symptoms arise. Follow your healthcare provider’s guidance for scheduling.
What does a normal monocyte count feel like?
A normal monocyte count doesn’t typically cause symptoms. However, if you have unexplained fatigue, frequent infections, or other symptoms, discuss them with your provider. They may recommend further testing or adjustments to your treatment plan.
Can lifestyle changes affect monocyte counts?
Yes, lifestyle factors like diet, exercise, and stress can influence white blood cell counts, including monocytes. Maintaining a balanced diet, staying hydrated, and managing stress may support overall immune health, but this test alone won’t show direct lifestyle impacts.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy