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Monocyte count (peripheral blood)

Published: August 9, 2026Updated: August 16, 2026

This test measures the number of monocytes, a type of white blood cell that helps your body fight infections and respond to inflammation.

Quick summary

["Monocytes help protect your immune system and may rise or fall depending on health conditions or treatments."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
74400-3
Short code
Monocytes NFr BldCo
Synonyms
Monocytes NFr BldCo
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why Might This Test Be Done?

Your healthcare provider may order a monocyte count to check for infections, inflammatory diseases, or blood disorders. It can also help monitor conditions like leukemia, autoimmune diseases, or reactions to certain medications.

What Does a High or Low Count Mean?

High levels of monocytes may suggest chronic infections, inflammation, or certain cancers. Low levels might indicate immune suppression, certain blood disorders, or side effects from treatments like chemotherapy.

How Is This Test Performed?

A small amount of blood is drawn from a vein in your arm. The sample is then analyzed to count the number of monocytes in your blood.

What Are Common Causes of Changes?

Changes in monocyte levels can occur due to infections (like tuberculosis), autoimmune diseases (like rheumatoid arthritis), or medical treatments affecting the immune system.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Monocyte level

Frequently asked questions

What does a normal monocyte count feel like?
A normal monocyte count is typically within the range your provider considers healthy for you. You may not experience any symptoms unless your levels are significantly elevated or low, which could cause fatigue, infections, or other symptoms.
Can lifestyle changes affect monocyte levels?
While diet, exercise, and stress management can influence overall immune health, they may not directly alter monocyte counts. However, maintaining good health can help your body function optimally.
How often should I get this test?
Your provider will determine how often you need this test based on your health status, symptoms, and medical history. Follow their guidance for scheduling.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy